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CAS Number: 1483-07-4
NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM)
m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
3-Deazaadenosine has anti-inflammatory
CCOC1=CC2C(C=C1)=NC1C=C(N)C=CC=1C=2N
DS-437 Catalog No.:M27732-C CAS Number: 1483-07-4DS 437 is a dual PRMT5 7 inhibitor (IC50s of PRMT5 7=6 M). DS 437 is selective for PRMT5 and PRMT7 over 29 other human protein , DNA , and RNA methyltransferases. DS 437 is a S adenosylmethionine (SAM) competitive inhibitor of PRMT5. DS 437 also inhibits DNMT3A and DNMT3B, with IC50s of 52 and 62 M, respectively. DS 437 inhibits the methylation of FOXP3. Product information CAS Number: 1674364 87 4 Molecular Weight: 397. 45 Formula: C15H23N7O4S
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