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Like the thienopyridines prasugrel
inhibits oxidative stress and inflammation in 2
a fungal infection of the nail and nail bed
1093/bioinformatics/bts702
Chemical Name: sodium 2-((4-(3-methoxyphenyl)-5-(pyridin-2-yl)-4H-1
R406 free base Catalog No.:M10764-10 Like the thienopyridines prasugrelTamatinib, also known as R 406, is a potent inhibitor of Syk with IC50 of 41 nM. R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin PF4 complex directed antibodies. R406 blocks fc receptor signaling and reduces immune complex mediated inflammation. R406 inhibited phosphorylation of Syk substrate linker for activation of T cells in mast cells and B cell linker protein SLP65 in B cells. R406 bound to the ATP
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